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Oxiracetam has had the most widespread use in Italy, where it was developed in 1988 by ICF, an Italian drug company. In the U.S., use has not been approved by the FDA. Smith Kline Beckman Corporation is trying to get the drug approved for treating Alzheimer’s disease.

But when these three unique brain-boosting nutrients are combined, they provide what you might call a “trifecta” of benefits that optimize brain and cognitive function like no other supplement on the face of the earth. So let’s talk briefly about these three highly specialized ingredients:

Jump up ^ Wong, Y. Nancy; Wang, Lixia; Hartman, Linda; Simcoe, Donna; Chen, Yusong; Laughton, Watson; Eldon, Richard; Markland, Colin; Grebow, Peter (1998). “Comparison of the Single-Dose Pharmacokinetics and Tolerability of Modafinil and Dextroamphetamine Administered Alone or in Combination in Healthy Male Volunteers”. The Journal of Clinical Pharmacology. 38 (10): 971–978. doi:10.1002/j.1552-4604.1998.tb04395.x. ISSN 0091-2700.

That doesn’t necessarily mean all smart drugs – now and in the future – will be harmless, however. The brain is complicated. In trying to upgrade it, you risk upsetting its intricate balance. “It’s not just about more, it’s about having to be exquisitely and exactly right. And that’s very hard to do,” says Arnstein. “What’s good for one system may be bad for another system,” adds Trevor Robbins, Professor of Cognitive Neuroscience at the University of Cambridge. “It’s clear from the experimental literature that you can affect memory with pharmacological agents, but the problem is keeping them safe.”

Because Dilantin influences electric currents, it can affect thinking and recall. Scientists don’t really understand how phenytoin works; however, they postulate that it influences electromagnetic fields, which polarize the electrically charged elements in the cells. This results in a more effective organizational structure, so that cell and brain functioning is improved.

PS is food for your brain cell membranes. Much of your brain’s cell membranes are made up of PS and, with supplementation, you may see improvements in a wide variety of cognitive functions that tend to decline with age such as: memory, learning, concentration, general mood, and alertness. PS is also particularly effective at reducing the ill effects of stress and helps keep cortisol levels down (important for long term anti-aging purposes.) Dosage: start at 200 – 300 mg for one month, then taper down to 100 mg per day.

Every assertion we make in this book is based on scientific research. We have provided references to this scientific literature throughout this book so that you may review the original research. However, to avoid disrupt­ing the flow of text we deviate slightly from scientific editorial conventions. When we refer to a research paper in the text, we give only the first author’s name and year of publication. The complete reference, with all authors, is given at the end of each chapter.

Though the popularity of nootropics have increased tenfold in the past few years, due in large part to massive media hits like Limitless, public knowledge of the reality of nootropics remains astonishingly low. Thus, it is fitting that this guide begins with a basic introduction into what constitutes a nootropic.

I bought this product looking for an affordable nootropic stack centered around Alpha-GPC and have been blown away by how well this delivered. I don’t know whether or not this is a placebo effect, but since I have been taking this I honestly feel like I can push myself for an extra hour or two of studying each day.

Noopept is often grouped together with the racetams, though its mechanism of action may be different. It is considered to be somewhere between 500-1000x more potent than Piracetam, making the amount needed per dose extremely miniscule.

As mentioned, smart drugs are anything that improves cognitive function and brain health. Within the nootropic community, these are categorized as compounds that interact with the users brain chemistry to improve specific cognitive functions.

Why brain hackers use it: The FDA has approved modafinil for the treatment of narcolepsy, but people without the condition take it to feel more alert, improve motivation and reaction time, and enhance mental function.

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